Order Megalis 20Mg Tablet Online
Order Megalis 20Mg Tablet, Tadalafil is used to treat the symptoms of erectile dysfunction (impotence) and benign prostatic hyperplasia. you can buy Megalis 20Mg Tablet online from Sex Medicine Shop.
Order Megalis 20Mg Tablet use side effects.
Headache, indigestion, dizziness, flushing, swelling of eyelids, eye pain, conjunctival hyperemia, back pain, muscle pain, blurred vision, nasal congestion, sudden hearing loss or hearing loss, tinnitus. Possibly fatal. Stevens-Johnson syndrome, exfoliative dermatitis, and serious cardiovascular events (e.g., myocardial infarction, stroke, or sudden cardiac death) may occur.
Megalis 20 mg 4s Tablet Drug interactions.
Increased risk of hypotension with concomitant use of α-blockers, increased risk of priapism with concomitant use of other erectile dysfunction drugs (e.g., alprostadil), increased heart rate with the use of fifpirine, decreased serum concentration of tadalafil with concomitant use of CYP 3A4 inducers (e.g., tadalafil).
E.g., rifampin, efavirenz, carbamazepine, nevirapine, barbiturates, phenobarbital, phenytoin, ribavirin; increased serum concentrations of tadalafil with concomitant use of CYP 3A4 inhibitors (e.g., azoles, protease inhibitors, cimetidine, macrolides). . Mortality. Hypotensive effects are potentiated by nitrates and nicorandil.
Contraindications to Order Megalis 20Mg Tablet
Concurrent use of organic nitrates, nitrates, and nitric oxide donors. Men with heart disease in whom sexual activity is not indicated. Recent myocardial infarction (within 90 days) or stroke (within the past 6 months), hypotension (<90/50 mmHg), unstable angina, heart failure, uncontrolled arrhythmia, hypertension.
Mechanism of action of Megalis 20 mg Tablet 4S.
Tadalafil is a phosphodiesterase type 5 inhibitor. The onset of action: 30 minutes Duration: 30 minutes to 36 hours. Absorption. Well Absorbed. Maximum plasma concentration is reached within 2 hours. The rate and extent of absorption are not affected by diet. Distribution. Distribution does not affect absorption.
Widespread tissue distribution; binds 94% to plasma proteins. Metabolism: Metabolized in the liver primarily by the CYP3A4 isoenzyme of cytochrome P450 to inactive metabolites. The average half-life is 17.5 hours. Excretion. Excreted primarily as metabolites in feces (61% of dose) and to a lesser extent in the urine (36% of dose).
Special precautions for Megalis 20 mg Tablets
Impaired liver or kidney function, cardiovascular disease, anatomical malformations of the penis, the tendency to priapism, children under 18 years of age. If you experience a sudden loss of vision in one or both eyes, ringing in the ears, dizziness, or sudden hearing loss while taking tadalafil, stop taking the medication and consult a doctor. If an erection lasts longer than 4 hours, see a doctor immediately.